Human Gene Prevents Regeneration in Zebrafish
UCSF Pomerantz Lab - November 18, 2015
UCSF News reports on new research of the Pomerantz Lab suggesting that future efforts to regrow or regenerate human tissue may require blocking the activity of a tumor-suppressor gene, ARF. The research involved adding the human ARF gene to a zebrafish, which prevented its normal ability to regenerate tissue, here the fish's tail fin that had been cut off.
The research was led by Jason Pomerantz, MD, Associate Professor of Surgery in the Division of Plastic and Reconstructive Surgery, Surgical Director of the UCSF Craniofacial Center, and Director of the Pomerantz Lab. The lead author on the [...]